Endocrine Abstracts

Ectopic mediastinal parathyroid adenoma is a rare cause of primary hyperparathyroidism (PHPT), which is reported in 1-1.5% of patients. We present you a case of a 22-year old male, who was suffering from severe itchiness which significantly interferes with his daily activities of life. His laboratory results were suggestive of PHPT (Table 1). His initial scans, including Technetium-99m (Tc-99m) Sestamibi (Mibi) did not reveal any abnormality. Subsequently, increase of PTH leve...

Neuroendocrine tumors (NETs) of the breast are very rare. They represent less than 1% of breast carcinomas. It is important to differentiate metastatic neuroendocrine neoplasia from primary neuroendocrine neoplasia of the breast. Histopathological misinterpretation of a breast NET is common. In a study of 18 NET cases that metastasized to the breast, it was found that 62% of these tumors originated from the gastrointestinal tract and 28% from the lung. Forty-four percent of th...

Objective: Familial hypercholesterolemia (FH) is a life-threatening genetic disease associated with elevated low density lipoprotein cholesterol (LDL-C) and premature coronary heart disease that is globally underdiagnosed and undertreated. This study aimed to search for the demographical characteristics, awareness and treatment adherence of underdiagnosed or undertreated FH patients from the records of the central biochemistry laboratory.Methods: Patient...

Objective: Radioactive iodine (RAI) treatment has been reported to be associated to increased cardiovascular events and death compared to the general population, but the mechanism is not fully understood. Endothelial dysfunction, inflammation, and insulin resistance play important roles in the pathogenesis of atherosclerotic events. We aimed to compare papillary thyroid carcinoma patients receiving levothyroxine suppression therapy after bilateral total thyroidectomy with or w...